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Apixaban is approximately 25% renally cleared and 75% metabolized through hepatic and intestinal pathways, with CYP3A4 serving as the dominant enzyme and O-demethylation as the primary reaction (NEJM, Granger et al., 2011) [3]

Particle size analysis was conducted using a Malvern Zetasizer Nano ZS instrument

In the event of an emergency, call 911 or go to the nearest Emergency Room.

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